CoaScoreA gauge with a check mark followed by the CoaScore wordmark CoaScore

See what the COA proves. Spot what it leaves out.

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For research use only · not medical advice

1 · Start with the actual report

Drop a COA image or PDF — we'll read what we can and you fill the rest

OCR makes mistakes, especially on scans and chromatograms. Check every field before scoring.

2 · What the paperwork supports

–/5

Ask the vendor for these missing pieces

    Four terms that should not be blurred together

    The short version

    Look for a named independent lab, a report number, a date, and the exact lot on the vial. HPLC purity needs its chromatogram. MS identity needs an observed mass that agrees with the expected molecule; semaglutide, for example, is about 4,113 Da. Net peptide content answers a different question: how much of the vial mass is peptide rather than salt and water. COAs we've looked at often skip that line.

    Glossary
    HPLC area purity
    The target peak's area as a percentage of all integrated peak area under that method. It is relative detector response, not mass-% of the vial. A bare 99% without a chromatogram is weak evidence; an unexplained 100.0% deserves extra scrutiny.
    Mass spec (MS) identity
    Compares an observed molecular mass with the compound's expected mass. A close match supports identity, but does not establish purity or vial quantity.
    Net peptide content
    The portion of vial mass attributed to peptide after components such as salt and water are accounted for. At 80% net, a 10 mg labeled amount corresponds to 8 mg of peptide.
    Salt form
    Peptides may be supplied as salts such as acetate or TFA. The counterion contributes mass, which is one reason area-% and net peptide content are different measurements.
    How to independently verify a COA

    Take the issuer and report number from the document, find the lab's official site yourself, and use its verification process where available. Janoshik reports, for example, may include a verification path. A vendor-hosted image is still only a vendor-hosted image.